Zylexx SR (150mg) 20 Tablets

Bupropion 150mg tablets primarily act as a norepinephrine-dopamine reuptake inhibitor (NDRI). Its mechanism of action involves blocking the reabsorption of two key neurotransmitters, norepinephrine and dopamine, in the brain. By inhibiting the reuptake of these neurotransmitters, bupropion increases their availability in the synaptic cleft, leading to enhanced neurotransmission. This increase in norepinephrine and dopamine activity is believed to play a crucial role in its therapeutic effects, particularly in the treatment of depression and smoking cessation. Bupropion's ability to modulate these neurotransmitter systems contributes to its effectiveness in regulating mood, motivation, and the rewarding aspects of nicotine addiction.

Bupropion 150mg

Antidepressant

Tablet

The following are the uses of Bupropion 150mg Tablet:

• Used for treating depression and helping to improve mood, feelings of well-being, and emotions.
• Used for supporting smoking cessation by reducing cravings and withdrawal symptoms.
• Used for seasonal affective disorder (SAD) treatment, a type of depression related to seasonal changes.
• Used for increasing focus and reducing impulsivity in attention-deficit/hyperactivity disorder (ADHD).
• Used for managing mood disorders, providing a stabilizing effect on emotions.
• Used for reducing the urge to engage in harmful behaviors, aiding in impulse control.
• Used for enhancing the effectiveness of other medications in certain mental health treatments.
• Used for assisting in the management of certain psychiatric conditions as part of a comprehensive treatment plan.

In the case of an overdose of Bupropion 150mg Tablets, individuals may experience symptoms such as seizures, rapid heartbeat, confusion, and hallucinations. It is important to recognize that the severity of these symptoms can vary based on the amount ingested. If an overdose is suspected, seeking immediate medical assistance is crucial. Prompt treatment can help manage the symptoms and prevent potential long-term complications. Time is of the essence in such situations, and quick action can make a significant difference in the outcome.

In the case of a missed dose of Bupropion 150mg Tablet, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. It is recommended to set a daily routine or use reminders to help you remember to take your medication at the same time each day. If you frequently miss doses, consult your healthcare provider for advice on how to improve your medication adherence.

To take Bupropion 150mg Tablets, swallow one tablet whole with a full glass of water, preferably in the morning or as directed by your healthcare professional, and do not crush, chew, or split the tablet.

Following are the conditions or situations when Bupropion 150mg Tablet should not be taken:

• Should not be taken by individuals with a known hypersensitivity or allergy to Bupropion or other similar antidepressants.
• Contraindicated in patients with a history of seizures or epilepsy, as it may lower the seizure threshold.
• Not suitable for individuals with an eating disorder, such as anorexia or bulimia.
• Should be avoided in patients with a recent history of head injury or brain trauma.
• Not recommended for patients who have suddenly stopped using alcohol, sedatives, or other medications that could cause withdrawal symptoms.
• Should not be used in individuals with untreated narrow-angle glaucoma.
• Contraindicated in patients with a history of bipolar disorder, as it may induce a manic episode.
• Avoid use in patients with severe hypertension (high blood pressure).
• Should not be taken by individuals with a history of liver or kidney disease.

The side effects of Bupropion 150mg Tablet may include:

• Nausea and vomiting
• Dry mouth
• Headache
• Dizziness
• Insomnia (difficulty in sleeping)
• Anxiety
• Skin rashes
• Increased heart rate

Following are the precautions and warnings for Bupropion 150mg Tablet:

• Individuals with a history of seizures or eating disorders should exercise caution and consult a healthcare professional before taking this medication.
• Not recommended for patients with a history of head injury or brain damage, as it may increase the risk of seizures.
• Patients with a history of bipolar disorder should be closely monitored for symptoms of mania or hypomania while on this medication.
• Avoid alcohol consumption while taking Bupropion, as it may increase the risk of seizures and adverse effects.
• Patients should not abruptly stop taking the medication without consulting their doctor, as it may lead to withdrawal symptoms.
• Caution is advised in patients with liver or kidney problems, as dosage adjustments may be necessary.
• Bupropion may cause allergic reactions; seek medical attention if you experience symptoms like rash, itching, or difficulty breathing.
• This medication should be used with caution in elderly patients, as they may be more sensitive to its effects.

Following are the drug interactions for Bupropion 150mg Tablet:

• Alcohol and other central nervous system (CNS) depressants can enhance the sedative effects of Bupropion, leading to increased drowsiness and impaired motor skills.
• Bupropion can increase the risk of seizures when combined with other medications that lower the seizure threshold, such as certain antidepressants (e.g., tricyclic antidepressants, SSRIs) or antipsychotics.
• The effectiveness of Bupropion may be reduced when taken with drugs that induce certain liver enzymes (e.g., carbamazepine, phenytoin), resulting in lower blood levels of Bupropion.
• Caution is advised when combining Bupropion with sympathomimetic drugs (e.g., epinephrine, pseudoephedrine), as it may increase blood pressure and heart rate.
• Bupropion may interact with nicotine replacement therapies, potentially increasing the risk of side effects such as hypertension and cardiovascular events.
• The use of Bupropion with other medications that affect serotonin levels (e.g., SSRIs, SNRIs) can lead to a condition called serotonin syndrome, characterized by agitation, confusion, and muscle rigidity.
• Anticoagulants such as warfarin may have their effects altered by Bupropion, requiring close monitoring of blood clotting times.

Following are the food interactions for Bupropion 150mg Tablet:

• Avoid excessive consumption of foods high in tyramine, such as aged cheeses, cured meats, and certain types of beer, as Bupropion can interact with tyramine and lead to increased blood pressure.
• Alcohol may enhance the sedative effects of Bupropion, so it's advisable to limit or avoid alcohol intake to prevent excessive drowsiness and impaired coordination.
• Grapefruit juice should be consumed with caution as it can affect the metabolism of Bupropion, potentially leading to increased drug levels in the blood and a higher risk of side effects.
• Consuming a high-fat meal with Bupropion may slightly decrease its absorption, but this effect is generally not clinically significant.
• It is generally recommended to take Bupropion with a full glass of water to aid in swallowing and reduce the risk of throat irritation.
• No significant interactions with specific food groups have been identified, but maintaining a balanced diet is always advisable for overall health.
• Always follow the dosing instructions provided by your healthcare professional, and consult them if you have any concerns about potential food interactions.

Bupropion 150mg Tablets should be stored in a secure and dry location, away from moisture and heat. Keep the medication in its original container, tightly sealed, to maintain its integrity and prevent contamination. It is crucial to store the tablets at room temperature, avoiding extreme temperatures. Regularly check the expiration date, and dispose of any unused or expired tablets promptly. When disposing of the medication, do not flush it down the toilet or pour it into drainage systems. Instead, follow local guidelines or consult a pharmacist for appropriate disposal methods to protect the environment. Ensure that the tablets are kept out of the reach of children and pets to prevent accidental consumption.

Following are the quick tips for Bupropion 150mg Tablet:

• Start with a lower dose and gradually increase as prescribed by your doctor.
• Take the tablet with a full glass of water to aid in swallowing.
• Bupropion is usually taken 2-4 times a day, ensure you space out the doses evenly.
• It's best to take the tablet at the same time each day to maintain a consistent routine.
• Avoid crushing or chewing the tablet; swallow it whole for optimal absorption.
• Do not stop taking the medication without consulting your doctor to prevent withdrawal symptoms.
• Store the tablets in a cool, dry place, away from direct sunlight and moisture.