Zurig (80mg) 20 Tablets

Febuxostat works by inhibiting xanthine oxidase, an enzyme that plays a key role in the production of uric acid from purines. By blocking this enzyme, febuxostat reduces the production of uric acid, which in turn lowers serum uric acid levels in the body. This helps prevent the formation of uric acid crystals, which are responsible for causing gout attacks and other related conditions. By decreasing uric acid levels, febuxostat helps manage hyperuricemia and the complications associated with it, such as gout flare-ups and urate crystal deposition.

Febuxostat 80mg

xanthine oxidase inhibitors

Tablet

The following are the uses of Febuxostat 80mg Tablet:

• Treatment of gout by lowering uric acid levels in the blood.
• Management of hyperuricemia associated with gout, reducing the frequency and severity of gout attacks.
• Prevention of gout-related complications such as tophi (deposits of uric acid crystals under the skin) and kidney stones.
• Used in patients who have had an inadequate response to allopurinol or are intolerant to it.

Following are the doses of Febuxostat 80mg Tablet:

• The usual dose for treating gout in adults is 80mg once daily.
• In patients who are not achieving adequate uric acid control, the dose may be increased to 120mg once daily, as prescribed by the healthcare provider.
• The medication should be taken once a day, with or without food.

In the case of an overdose of Febuxostat 80mg Tablet, immediate medical attention should be sought.Overdose may lead to symptoms such as nausea, vomiting, or abdominal discomfort. If too much medication is taken, it is important to contact a healthcare provider for proper evaluation and guidance. Do not attempt to induce vomiting or take any other actions without consulting a healthcare provider. It is essential to follow the prescribed dosage and avoid exceeding the recommended dose to prevent any adverse effects.

If you miss a dose of Febuxostat 80mg Tablet, take it as soon as you remember.However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses at the same time to make up for the missed dose, as this may increase the risk of side effects

To use Febuxostat 80mg Tablet, follow the instructions provided by your healthcare provider or as indicated on the prescription label.Typically, the tablet should be taken once daily, with or without food. Swallow the tablet whole with a glass of water. Do not chew, crush, or break the tablet. It is important to take the medication at the same time each day to help you remember and maintain consistent levels in your body.

Following are the situations when Febuxostat 80mg Tablet should not be used:

• Should not be used in individuals with a known allergy to Febuxostat or any of its ingredients.
• Contraindicated in patients with severe liver impairment.
• Not recommended in patients with a history of cardiovascular disease, such as a recent heart attack or unstable angina, without consulting a healthcare provider.
• Should not be used in patients with an active gout flare unless advised by a healthcare provider.

The side effects of Febuxostat 80mg Tablet may include:

• Headache
• Nausea
• Liver enzyme elevation
• Diarrhea
• Rash
• Joint pain
• Gout flare-ups during initial treatment
• Dizziness
• Fatigue
• Heart-related issues in some patients

Following are the precautions and warnings for Febuxostat 80mg Tablet:

• Should not be used in individuals with a known allergy to Febuxostat or any of its ingredients.
• Caution is advised in patients with a history of liver or kidney disease, as the medication can impact liver function and kidney health.
• Use with caution in patients with a history of heart disease, as Febuxostat may increase the risk of cardiovascular events.
• Regular monitoring of liver function and uric acid levels is recommended during treatment with Febuxostat.
• Avoid concurrent use with strong inhibitors of xanthine oxidase (such as allopurinol) as this may increase the risk of side effects.
• Not recommended for use during pregnancy or breastfeeding unless prescribed by a healthcare provider. Always consult your healthcare provider before starting treatment.

Following are the drug interactions for Febuxostat 80mg Tablet:

• Co-administration with mercaptopurine or azathioprine (drugs that are metabolized by xanthine oxidase) may increase the risk of severe side effects, as Febuxostat can inhibit xanthine oxidase.
• Use with theophylline may lead to increased theophylline levels in the blood, requiring dose adjustments.
• Combined use with certain blood thinners like warfarin may increase the risk of bleeding, so regular monitoring of INR is advised.
• Febuxostat should be used with caution in combination with certain diuretics, as this could affect kidney function and uric acid levels.

Following are the food interactions for Febuxostat 80mg Tablet:

• Grapefruit and grapefruit juice may increase the levels of Febuxostat in the blood, potentially leading to an increased risk of side effects.
• It is advisable to avoid consuming large amounts of alcohol while taking Febuxostat, as alcohol may worsen gout symptoms and reduce the effectiveness of the medication.
• There are no major food interactions known, but maintaining adequate hydration may help reduce the risk of uric acid buildup during treatment.

Febuxostat 80mg Tablet should be stored at room temperature, away from moisture, heat, and direct sunlight. Keep the medication in its original container, tightly closed, and out of the reach of children. Do not store the tablets in the bathroom or in areas where they may be exposed to excessive heat or humidity. If the medication has expired or is no longer needed, dispose of it properly. Do not flush the tablets down the toilet or pour them into a drain unless instructed to do so. For proper disposal, you may consult your pharmacist or local waste disposal services.

Following are the quick tips for Febuxostat 80mg Tablet:

• Take Febuxostat exactly as prescribed by your healthcare provider to manage your uric acid levels effectively.
• It is best to take Febuxostat once daily, with or without food, at the same time each day to help you remember.
• Stay well-hydrated while on this medication to help reduce the risk of kidney stones.
• Avoid consuming alcohol or excessive purine-rich foods, as these can worsen gout symptoms.
• Regularly monitor your uric acid levels as instructed by your healthcare provider to ensure the medication is working effectively.
• If you experience any unusual symptoms like a rash or joint pain, contact your healthcare provider immediately.