My-D (50,000IU) 4 Tablets

Cholecalciferol, also known as vitamin D3, has a specific mechanism of action. When administered, it enters the bloodstream and undergoes two hydroxylation reactions in the body to become its active form, calcitriol (1,25-dihydroxyvitamin D3). The first hydroxylation occurs in the liver, converting cholecalciferol to 25-hydroxyvitamin D3 (calcifediol). This is followed by a second hydroxylation in the kidneys, where calcitriol is produced. Calcitriol acts as a hormone, binding to vitamin D receptors (VDRs) in various target cells, particularly in the intestines, bones, and kidneys. This binding activates specific genes, leading to increased intestinal absorption of calcium and phosphorus, promoting bone mineralization, and regulating calcium and phosphate homeostasis. By enhancing calcium absorption and utilization, cholecalciferol plays a crucial role in maintaining healthy bones and preventing conditions related to vitamin D deficiency.

Cholecalciferol 50,000iu

Vitamin D3 supplement

Tablet

The following are the uses of Cholecalciferol 50,000iu Tablet:

• Used for treating Vitamin D deficiency.
• Used to strengthen bones and prevent conditions like rickets and osteoporosis.
• Used in individuals with malabsorption syndromes to ensure proper nutrient absorption.
• Used to support immune function and reduce the risk of respiratory infections.
• Used to manage certain skin conditions like psoriasis.
• Used for individuals with limited sun exposure, especially during winter months.
• Used to improve muscle strength and overall physical performance.
• Used as a supplement during pregnancy for fetal bone development.

The following dosage regimen is to be followed:

• Adults

The Recommended Dietary Allowance for adults is 600 IU daily

• Geriatric

The RDA for people 70 years or above is 800 IU daily

• Children

To be used as per doctor's recommendation

In the case of an overdose of Cholecalciferol 50,000 IU tablets, the symptoms may include nausea, vomiting, constipation, loss of appetite, and fatigue. Excessive levels of vitamin D can lead to hypercalcemia, a condition characterized by elevated calcium levels in the blood. This can result in severe health issues such as kidney damage, heart arrhythmias, and even bone pain. It is crucial to seek medical advice promptly if an overdose is suspected, as treatment may involve supportive care and monitoring of calcium levels to prevent potential complications.

In the case of a missed dose of Cholecalciferol 50,000 IU Tablet, it is generally advised to take the missed dose as soon as you remember. However, if it's almost time for your next scheduled dose, it's best to skip the missed dose and continue with your regular dosing schedule. Avoid taking extra doses to make up for the missed one, as this may lead to excessive vitamin D levels in your body. If you frequently miss doses, consider setting reminders or asking someone to help you remember to take your medication as prescribed.

To take Cholecalciferol 50,000 IU Tablet, swallow the tablet whole with a glass of water, preferably with a meal or as directed by your healthcare professional, following the prescribed dosage and treatment duration as instructed by your doctor.

Following are the conditions or situations when Cholecalciferol 50,000iu Tablet should not be taken:

• Avoid if you have a known allergy to vitamin D or any of its components.
• Do not take if you have high levels of calcium in your blood (hypercalcemia) or urine (hypercalciuria).
• Contraindicated in individuals with kidney stones or a history of kidney disease.
• Not suitable for patients with conditions that cause hardening of tissues, such as granulomatous diseases.
• Should not be used in people with uncontrolled high blood pressure.
• Avoid if you have a condition called hypervitaminosis D, where vitamin D levels are already excessively high.
• Not recommended for those with conditions causing excessive calcium deposits in tissues (calcification).

The side effects of Cholecalciferol 50,000 IU Tablet may include:

• Nausea and vomiting.
• Diarrhea or constipation.
• Dry mouth.
• Fatigue and weakness.
• Muscle or joint pain.
• Increased thirst and urination.
• Skin rash or itching.
• Dizziness or lightheadedness.

Following are the precautions and warnings for Cholecalciferol 50,000 IU Tablet:

• Do not take this medication if you are allergic to vitamin D or any other ingredients in the tablet.
• Individuals with kidney disease or conditions affecting vitamin D metabolism should use this medication with caution and under medical supervision.
• Patients with hypercalcemia (high calcium levels) should not take this medication as it can worsen the condition.
• Cholecalciferol can cause elevated calcium levels in the blood; regular monitoring is necessary, especially for those at risk of hypercalcemia.
• This medication may interact with certain drugs, including digoxin, thiazide diuretics, and corticosteroids, so inform your doctor about all medications you are taking.
• Avoid excessive sun exposure as vitamin D increases sensitivity to sunlight and may cause sunburn.
• Do not exceed the recommended dosage as high doses of vitamin D can lead to serious side effects.
• Keep out of reach of children; accidental overdose can be harmful.

Following are the drug interactions for Cholecalciferol 50,000 IU Tablet:

• Thiazide diuretics can decrease the excretion of vitamin D, leading to potential hypercalcemia.
• Anticonvulsants like phenobarbital, phenytoin, and carbamazepine can reduce vitamin D levels, possibly requiring higher doses of Cholecalciferol.
• Cholestyramine and colestipol can decrease the absorption of vitamin D, potentially requiring dose adjustments.
• Orlistat can reduce the absorption of fat-soluble vitamins, including vitamin D, which may need supplementation.
• Calcium-containing antacids or calcium supplements can increase the risk of hypercalcemia when used with Cholecalciferol.
• Drugs that increase photosensitivity, such as thiazides and tetracyclines, may enhance the risk of hypercalcemia when used with vitamin D.
• Ketoconazole and other antifungal agents can increase the risk of hypervitaminosis D when used concurrently with Cholecalciferol.

Following are the food interactions for Cholecalciferol 50,000 IU Tablet:

• Consuming foods rich in Vitamin D, such as fatty fish (salmon, mackerel, tuna), egg yolks, liver, and fortified dairy products, alongside the tablet may lead to excessive Vitamin D intake, potentially causing hypervitaminosis D.
• Avoid high-fiber foods like whole grains, nuts, and legumes, as they may reduce the absorption of Vitamin D, decreasing the effectiveness of the medication.
• Limit calcium-rich foods like dairy products, as excessive calcium intake along with Vitamin D can lead to hypercalcemia.
• Grapefruit and grapefruit juice should be consumed cautiously as they may affect the metabolism of Vitamin D, potentially altering its levels in the body.
• Avoid excessive alcohol consumption as it may interfere with Vitamin D metabolism and reduce the effectiveness of the medication.
• Vitamin D is a fat-soluble vitamin, so ensure the tablet is taken with a meal containing healthy fats to enhance its absorption.
• Certain medications, like orlistat and cholestyramine, can reduce Vitamin D absorption, so consult your healthcare provider if you're taking these concurrently.

Cholecalciferol 50,000iu Tablets should be stored in a cool and dry place, preferably at room temperature, ensuring protection from direct sunlight and moisture. Keep the tablets in their original packaging, tightly sealed, to maintain their integrity and prevent contamination. It is crucial to avoid exposing the medication to extreme temperatures, so steer clear of storage areas like bathrooms, near stoves, or on radiators. Always check the expiration date, and if the medication is no longer needed or has expired, proper disposal is essential. Do not dispose of it in sewage or drainage systems; instead, consult a pharmacist or healthcare professional for guidance on safe disposal methods. Keep the medication securely stored away from children to prevent accidental ingestion.

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Following are the quick tips for Cholecalciferol 50,000iu Tablet:

• Consult your doctor before taking this medication, especially if you have kidney or heart conditions.
• Take the tablet as directed by your healthcare provider, typically once a week or as prescribed.
• Consume the tablet with a full glass of water for easy swallowing.
• Maintain a consistent schedule for taking the medication for best results.
• Avoid missing doses; if you miss a dose, take it as soon as you remember, unless it's almost time for your next dose.
• Do not double the dose to make up for a missed one.
• Store the tablets in a cool, dry place, away from direct sunlight and moisture.