Efroxil (125mg/5ml) 60ml Dry Suspension

Cefadroxil is a first-generation cephalosporin antibiotic that exerts its bactericidal effect by inhibiting cell wall synthesis in susceptible bacteria. It specifically targets penicillin-binding proteins (PBPs), which are essential for cross-linking peptidoglycan strands in the bacterial cell wall. By binding to these PBPs, Cefadroxil interferes with the final stages of cell wall synthesis, leading to the weakening and eventual lysis of the bacterial cell wall. This mechanism disrupts the structural integrity of the bacteria, resulting in their death. Cefadroxil has a broad spectrum of activity against both gram-positive and gram-negative bacteria, making it effective in treating a range of infections caused by susceptible organisms.

Cefadroxil 125mg

Cephalosporin antibiotic

Suspension

The following are the uses of Cefadroxil 125mg Syrup/Suspension:

• Used for treating bacterial infections in children, particularly ear infections, such as acute otitis media.
• Used for respiratory tract infections like pneumonia and bronchitis in children.
• Effective for skin and soft tissue infections, including cellulitis and impetigo.
• Used for preventing infections post-surgery or in cases of weakened immune systems.
• Helps manage bone and joint infections, including osteomyelitis.
• Treats urinary tract infections (UTIs) caused by susceptible bacteria.
• Provides relief for mild to moderate infections, ensuring a swift recovery.

Tailoring Treatment for Optimal Health, Prescribed Medication Dosage is:

• Acute bacterial sinusitis- 250 mg every 12 hours for 7-14 days
• Acute bacterial otitis media- 30 mg/kg once daily for 7 days
• Pharyngitis/tonsillitis- 250 mg every 6 hours for 7 days
• Mild to moderate pneumonia- 500 mg initially, then 250 mg every 12 hours for 7-14 days
• Skin and skin structure infections- 250 mg every 6 hours for 7 days

In the case of an overdose of Cefadroxil 125mg Syrup/Suspension, the primary concern is the potential for gastrointestinal symptoms such as nausea, vomiting, and diarrhea. These symptoms may occur due to the high concentration of the antibiotic in the digestive system. It is crucial to contact a healthcare professional or poison control center promptly for guidance on managing the overdose, as they can provide specific instructions based on the patient's age, weight, and overall health.

In the case of a missed dose of Cefadroxil 125mg Syrup/Suspension, it is important to take the missed dose as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for guidance on how to proceed with your medication regimen.

To administer Cefadroxil 125mg Syrup/Suspension, shake the bottle vigorously, measure the prescribed dose with a marked measuring cup or oral syringe, and give it to the patient orally, following the dosage instructions provided by your healthcare professional, typically taken every 12 hours, regardless of meals.

Here are the conditions and situations when Cefadroxil 125mg Syrup/Suspension should not be used:

• Avoid in individuals with a known allergy to Cefadroxil or other cephalosporin antibiotics.
• Not suitable for patients with a history of severe allergic reactions to penicillins.
• Contraindicated in patients with severe kidney disease or impairment.
• Should not be used if the patient has a history of gastrointestinal diseases, especially colitis.
• Not recommended for individuals with a history of seizures or conditions that increase the risk of seizures.
• Avoid in newborns with jaundice or hyperbilirubinemia.
• Do not use if the patient has a history of severe diarrhea caused by antibiotics.
• Contraindicated during breastfeeding as it may pass into breast milk.

The side effects of Cefadroxil 125mg Syrup/Suspension may include:

• Nausea and vomiting
• Diarrhea
• Abdominal pain or discomfort
• Skin rash or itching
• Allergic reactions (hives, swelling, difficulty breathing)
• Headache
• Dizziness
• Vaginal itching or discharge

Following are the precautions and warnings for Cefadroxil 125mg Syrup/Suspension:

• This medication should not be used in individuals with a known allergy to Cefadroxil or other cephalosporin antibiotics.
• Always complete the full course of antibiotic treatment, even if symptoms improve before completion.
• Cefadroxil may cause diarrhea; if severe or persistent, it may indicate a more serious condition, and medical advice should be sought.
• Patients with a history of gastrointestinal diseases like colitis should be closely monitored while on this medication.
• May affect certain lab tests, so inform your doctor if you are taking this medicine before any tests.
• Caution is advised for patients with kidney or liver problems, as dosage adjustments may be necessary.
• Not recommended for use in infants below 3 months of age.
• Consult a healthcare professional if you are pregnant, breastfeeding, or planning to become pregnant before taking this medication.

Following are the drug interactions for Cefadroxil 125mg Syrup/Suspension:

• Probenecid may decrease the elimination of Cefadroxil, leading to increased levels and potential toxicity.
• Concomitant use with methotrexate may decrease methotrexate clearance, increasing its toxicity.
• Cefadroxil may reduce the effectiveness of oral contraceptives, requiring additional contraceptive measures.
• Alcohol may interfere with the absorption and effectiveness of Cefadroxil, and should be avoided.
• When taken with antacids containing aluminum or magnesium, Cefadroxil absorption may be reduced, and separate dosing is recommended.
• May decrease the efficacy of live attenuated vaccines, such as the oral polio vaccine, due to its antibacterial effect.
• The potential for increased adverse effects exists when used with other antibiotics, such as aminoglycosides, due to overlapping side effect profiles.

Following are the food interactions for Cefadroxil 125mg Syrup/Suspension:

• Avoid consuming alcohol during the treatment period as it may reduce the effectiveness of Cefadroxil and increase the risk of side effects like dizziness and stomach discomfort.
• Grapefruit and grapefruit juice should be consumed with caution as they can interfere with the metabolism of Cefadroxil, potentially leading to increased drug levels in the body and a higher risk of side effects.
• Dairy products like milk, yogurt, and cheese may reduce the absorption of Cefadroxil. Consider taking the medication at least 1-2 hours before or after consuming dairy.
• Iron-rich foods like red meat, spinach, and beans can decrease the absorption of Cefadroxil. It is recommended to separate the medication and these foods by a few hours.
• High-fiber foods like whole grains, legumes, and nuts may delay the absorption of Cefadroxil. Ensure you take the medication on an empty stomach or with a light meal.
• Vitamin and mineral supplements, particularly those containing iron, zinc, or calcium, can interfere with Cefadroxil absorption. Take the medication at least 2 hours before or after taking supplements.
• Avoid consuming large amounts of caffeine while taking Cefadroxil, as it may increase the risk of side effects like insomnia and nervousness.
• Follow the dosage instructions provided by your healthcare professional, and ensure you complete the full course of treatment to maximize effectiveness.

Cefadroxil 125mg Syrup/Suspension should be stored in a cool and dry environment, preferably at room temperature, ensuring it is shielded from direct sunlight and moisture. Maintain the medication in its original tightly sealed container to prevent contamination. Steer clear of storage in bathrooms or areas exposed to heat, as temperature fluctuations can impact the medication's integrity. Prior to usage, verify the expiration date on the packaging, and responsibly dispose of any unused or expired syrup; refrain from flushing it or pouring it down the drain. Consult your pharmacist or healthcare provider for guidance on appropriate disposal methods. Additionally, exercise caution to keep the medication inaccessible to children to prevent accidental ingestion.

Following are the quick tips for Cefadroxil 125mg Syrup/Suspension:

• Administer the prescribed dosage as instructed by your healthcare professional for effective treatment.
• Ensure you shake the bottle thoroughly before each use to maintain a well-mixed suspension.
• Take the syrup with a full glass of water for better absorption.
• Maintain a consistent schedule by taking the medication at the same time daily.
• Store the syrup in a cool, dry place, away from direct sunlight and moisture.
• Always check the expiration date before using the medication.
• Do not share this medication with others, even if their symptoms resemble yours.