Dapa (10mg) 28 Tablets

Dapagliflozin's primary mechanism of action is to inhibit the sodium-glucose cotransporter 2 (SGLT2) in the proximal tubule of the kidney. By blocking SGLT2, it reduces the reabsorption of glucose from the glomerular filtrate, leading to increased glucose excretion in the urine (glucosuria). This lowers blood glucose levels by promoting the removal of excess glucose from the body, independent of insulin secretion or action. Dapagliflozin's effect on SGLT2 also results in mild osmotic diuresis, which can contribute to its overall glucose-lowering and potential weight-loss effects.

Dapagliflozin 10mg

SGLT-2 inhibitor.

Tablet

The following are the uses of Dapagliflozin 10mg Tablet:

• Used for treating Type 2 Diabetes
• Used to improve glycemic control
• Used to lower blood sugar levels
• Used to reduce the risk of cardiovascular events in diabetic patients
• Used to manage weight in obese individuals
• Used to lower blood pressure in certain cases
• Used to improve kidney function in diabetic kidney disease

In the case of an overdose of Dapagliflozin 10mg Tablets, it is important to recognize the potential symptoms and take appropriate action. These symptoms may include dehydration, excessive urination, and severe dizziness. If an overdose is suspected, it is recommended to seek medical advice promptly. Treatment may involve supportive care, such as monitoring fluid and electrolyte levels, and managing any complications that arise from the overdose. Prompt recognition and response are crucial in managing Dapagliflozin overdoses effectively.

In the case of a missed dose of Dapagliflozin 10mg Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you frequently miss doses, it is advisable to set reminders or use a pill organizer to help you stay on track. It is also recommended to consult your healthcare provider for guidance on managing missed doses, especially if you miss several doses in a row.

To take Dapagliflozin 10mg Tablet, swallow the tablet whole with a full glass of water, preferably in the morning, as directed by your healthcare provider, and do not crush, chew, or break the tablet.

Following are the conditions or circumstances when Dapagliflozin 10mg Tablet should not be taken:

• Should not be used in patients with known hypersensitivity or severe allergic reactions to Dapagliflozin or any of the tablet's components.
• Contraindicated in patients with Type 1 diabetes mellitus or diabetic ketoacidosis.
• Not recommended for individuals with severe kidney disease or those on dialysis.
• Should not be used in patients with a history of a serious urinary tract infection or genital infection.
• Not suitable for individuals with a history of bladder cancer or other bladder-related conditions.
• Contraindicated during pregnancy and breastfeeding.
• Should be discontinued before any planned surgery.

The side effects of Dapagliflozin 10mg Tablet may include:

• Increased urination
• Thirst
• Genital yeast infections
• Urinary tract infections (UTIs)
• Low blood sugar (hypoglycemia)
• Nausea and vomiting
• Dizziness or lightheadedness
• Skin rashes or itching

Following are the precautions and warnings for Dapagliflozin 10mg Tablet:

• Patients with type 1 diabetes or diabetic ketoacidosis should not take this medication.
• Before taking this medication, inform your doctor if you have any kidney problems, as it may not be suitable for those with severe kidney disease.
• It can cause dehydration, so monitor for signs of dehydration and seek medical advice if needed.
• Patients with a history of genital or urinary tract infections should exercise caution, as this medication may increase the risk of such infections.
• Dapagliflozin may lead to a drop in blood pressure, especially in individuals with low systolic blood pressure.
• Elderly patients may require closer monitoring due to increased susceptibility to adverse effects.
• Patients with a history of bladder cancer or uncorrected anatomical abnormalities of the urinary tract should consult a doctor before taking this medication.
• If you experience any allergic reactions or severe side effects, discontinue use and seek medical attention immediately.

Following are the drug interactions for Dapagliflozin 10mg Tablet:

• Dapagliflozin may interact with diuretics, leading to increased diuresis and risk of dehydration.
• Risk of hypoglycemia is heightened when used with insulin or other antidiabetic medications. Close monitoring is necessary.
• Concomitant use with angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) may increase the risk of renal impairment.
• Avoid using Dapagliflozin with other SGLT2 inhibitors as it may lead to excessive glucose excretion and dehydration.
• Alcohol consumption can increase the risk of dehydration and hypotension when taking Dapagliflozin.
• The effectiveness of Dapagliflozin may be reduced when used with corticosteroids or beta-blockers, requiring careful monitoring.
• Certain medications affecting renal function, such as nonsteroidal anti-inflammatory drugs (NSAIDs), may require dosage adjustments when used alongside Dapagliflozin.

Following are the food interactions for Dapagliflozin 10mg Tablet:

• Dapagliflozin can be taken without regard to meals, but maintaining a consistent routine with food intake is generally recommended.
• Alcohol intake should be moderated as it can affect blood sugar levels and may increase the risk of side effects like dizziness.
• Avoid grapefruit and grapefruit juice as they may influence blood sugar control and interact with the medication's metabolism.
• Avoid high-sugar foods and beverages, as they can counteract the blood sugar-lowering effect of the medication.
• No significant direct food interactions are known, but it's advisable to consult your doctor or dietician for personalized dietary advice.
• Maintain a balanced diet with consistent carbohydrate intake to support the medication's effectiveness.
• Be cautious with salt and potassium-rich foods, as Dapagliflozin can affect electrolyte levels.

Dapagliflozin 10mg Tablets should be stored in a cool and dry place, preferably at room temperature, ensuring protection from light and moisture. It is crucial to keep the tablets in their original packaging, tightly sealed, to maintain their integrity and prevent exposure to external elements. Avoid placing the medication in the bathroom or near heat-emitting appliances, as temperature and humidity fluctuations can impact its effectiveness. Regularly check the expiration date, and dispose of any unused or expired tablets responsibly. Do not dispose of them via household waste or sewage systems; consult a pharmacist or healthcare professional for appropriate disposal guidelines. Additionally, ensure the medication is stored in a secure location, out of the reach of children, to prevent accidental consumption.

Following are the quick tips for Dapagliflozin 10mg Tablet:

• Take the tablet as directed by your doctor, usually once daily.
• Consume the tablet with a full glass of water.
• You can take it with or without food, but be consistent with your choice.
• If you experience mild dizziness, be cautious when standing up from a sitting or lying position.
• Inform your doctor if you have a history of liver or kidney problems.
• Regularly monitor your blood sugar levels as advised by your doctor.
• Store the tablets in a cool, dry place, away from direct sunlight.