COSMELAN PLUS CREAM 25G

Alpha Arbutin and Ascorbyl Tetraisopalmitate work synergistically in the Alpha Arbutin, Ascorbyl Tetiaisopalmitate Cream to address skin concerns effectively. Alpha Arbutin inhibits the activity of tyrosinase, a key enzyme in melanin production, thereby reducing the formation of dark spots and promoting a brighter complexion. On the other hand, Ascorbyl Tetraisopalmitate is a highly stable and lipid-soluble derivative of vitamin C. It penetrates the skin's layers, where it is converted to active vitamin C (L-ascorbic acid). This active form of vitamin C boosts collagen synthesis, inhibits melanin production, and provides powerful antioxidant protection against free radicals, helping to reduce the appearance of hyperpigmentation and improve overall skin tone and texture.

Alpha Arbutin, Ascorbyl Tetraisopalmitate

Depigmenting agent and Vitamin C derivative

Cream

The following are the uses of Alpha Arbutin, Ascorbyl Tetraisopalmitate Cream:

• Used for reducing dark spots, hyperpigmentation, and melasma
• Used for brightening and evening out skin tone
• Used to improve skin texture and enhance radiance
• Used for fading acne scars and sun damage
• Used as an antioxidant to protect skin from environmental stressors
• Used to enhance the effectiveness of other skincare ingredients
• Used for long-term skin lightening and maintenance
• Used in combination with other actives for comprehensive skincare routines

In the case of an overdose of Alpha Arbutin and Ascorbyl Tetraisopalmitate Cream, it is important to remain calm and seek medical advice promptly. Although rare, an overdose may cause skin irritation, redness, or increased sensitivity. Wash the affected area with mild soap and water if the product is applied topically. Contact a healthcare professional or a poison control center for further guidance on managing any potential side effects.

In the case of a missed dose of Alpha Arbutin, Ascorbyl Tetraisopalmitate Cream, it is recommended to apply it as soon as you remember. If it is close to the time for your next application, skip the missed dose and continue with your regular schedule. It is generally safe to apply the cream as soon as possible, but avoid applying extra to make up for the missed dose. Consult your dermatologist if you frequently miss doses to ensure you're using the product effectively.

To use Alpha Arbutin, Ascorbyl Tetraisopalmitate Cream, gently cleanse your face, pat dry, and apply a thin layer to the desired area once or twice daily, or as directed by your dermatologist, and avoid the eye area.

Following are the conditions/situations when Alpha Arbutin, Ascorbyl Tetraisopalmitate Cream should be avoided:

• Avoid using if you have a known sensitivity or allergy to any of the ingredients, including alpha arbutin, ascorbyl tetraisopalmitate, or other related compounds.
• Do not use on open wounds, cuts, or severely damaged skin.
• Avoid contact with eyes and mucous membranes.
• Not suitable for individuals with a history of skin conditions like eczema or dermatitis, unless advised by a dermatologist.
• Should not be used on skin with active inflammation or severe irritation.
• Discontinue use if you experience any adverse reactions such as severe itching, burning, or redness.
• Avoid using this cream on children's skin without medical advice.

The side effects of Alpha Arbutin, Ascorbyl Tetraisopalmitate Cream may include:

• Skin irritation or redness at the application site.
• Itching or stinging sensation.
• Dryness or peeling of the skin.
• Allergic reactions, such as rash, hives, or itching.
• Increased sensitivity to sunlight (photosensitivity).
• Darkening or lightening of the skin in rare cases.
• Acne or skin breakouts, especially with excessive use.
• Mild burning or tingling, particularly if used on sensitive skin.

Following are the precautions and warnings for Alpha Arbutin, Ascorbyl Tetraisopalmitate Cream:

• Avoid contact with eyes and mucous membranes; if contact occurs, rinse thoroughly with water.
• Perform a patch test on a small area of skin before using it on a larger area to check for any allergic reactions.
• Discontinue use and consult a dermatologist if irritation, redness, or any adverse reactions occur.
• Do not use on broken or damaged skin, and avoid direct sun exposure after application.
• Keep out of reach of children and pets.
• Store in a cool, dry place, away from direct sunlight and extreme temperatures.
• This product is for external use only and should not be ingested.

Following are the drug interactions for Alpha Arbutin, Ascorbyl Tetraisopalmitate Cream:

• No significant drug interactions have been reported with Alpha Arbutin, but it may interact with other topical agents, potentially enhancing skin sensitivity.
• Ascorbyl Tetraisopalmitate can enhance the absorption of other active ingredients, increasing their effectiveness.
• This cream may increase skin sensitivity when used with other exfoliating agents or retinoids.
• Avoid using with benzoyl peroxide, as it may degrade the stability of Ascorbyl Tetraisopalmitate.
• Use with caution alongside other Vitamin C derivatives to prevent potential skin irritation.
• The cream's efficacy may be reduced when combined with highly alkaline substances.
• Avoid using with substances that are unstable in the presence of ascorbic acid derivatives.

Following are the food interactions for Alpha Arbutin and Ascorbyl Tetraisopalmitate Cream:

• Citrus fruits like oranges, lemons, and limes should be consumed in moderation as they may cause mild skin irritation or increase sensitivity, especially when used alongside Alpha Arbutin.
• Avoid excessive sun exposure and consider using sunscreen as some ingredients may increase sun sensitivity.
• Dairy products with high lactose content might influence the effectiveness of Ascorbyl Tetraisopalmitate due to potential interactions with lactose enzymes.
• Green tea and black tea are rich in antioxidants and may enhance the skin-brightening effects of Alpha Arbutin.
• Foods rich in Vitamin C, such as bell peppers, broccoli, and strawberries, can support the effectiveness of Ascorbyl Tetraisopalmitate, promoting collagen synthesis.
• Garlic and onion, known for their sulfur-containing compounds, may have a positive impact on overall skin health when used alongside these skincare ingredients.
• Omega-3 fatty acids found in fish like salmon and mackerel can contribute to maintaining skin moisture and supporting the overall benefits of Ascorbyl Tetraisopalmitate.
• Avoid excessive consumption of processed foods and sugary snacks as they may negatively impact skin health and reduce the effectiveness of these skincare ingredients.

The storage and disposal of Alpha Arbutin, Ascorbyl Tetraisopalmitate Cream require specific attention. Store the cream in a cool, dry place, preferably at room temperature, ensuring it is protected from direct sunlight and moisture. Keep the cream tightly sealed in its original packaging to maintain its integrity and prevent contamination. Avoid extreme temperatures, including hot areas like near stoves or inside cars, as this can impact the cream's effectiveness. Check the expiration date regularly and dispose of expired or unused cream responsibly; do not pour it down the drain or flush it. Consult your pharmacist for appropriate disposal methods, and keep the cream away from children to prevent accidental exposure.

Following are the quick tips for Alpha Arbutin and Ascorbyl Tetraisopalmitate Cream:

• Apply a thin layer to the affected area as directed by your dermatologist.
• Use the cream as part of your skincare routine for even skin tone and texture.
• Cleanse your face before application to ensure better absorption.
• Avoid contact with eyes; rinse thoroughly with water if contact occurs.
• Store the cream in a cool, dry place, away from direct sunlight.
• Do not use on broken or irritated skin.
• Discontinue use if any adverse reaction occurs and consult your healthcare provider.