Canestan (1%) 20g Cream

Clotrimazole Cream primarily works by interfering with the integrity of the fungal cell membrane. It specifically targets a key component called ergosterol, which is essential for maintaining the structure and function of fungal cell membranes. The active ingredient in the cream, clotrimazole, binds to ergosterol, leading to the disruption and destabilization of the membrane. This disruption impairs the membrane's ability to regulate the movement of substances in and out of the cell, causing vital intracellular components to leak out. Consequently, the fungal cells lose their structural integrity, leading to cell lysis and death, effectively halting the progression of the fungal infection.

Clotrimazole

Antifungal

Cream

The following are the uses of Clotrimazole Cream:

• Used for treating fungal skin infections like athlete's foot, jock itch, and ringworm.
• Used for relieving itching, redness, and burning caused by these infections.
• Used for clearing fungal rashes and restoring healthy skin.
• Used for preventing the spread of fungal infections to others.
• Used for maintaining skin hygiene and preventing recurrence.
• Used for sensitive areas like the groin or between toes, offering gentle relief.
• Used for its broad-spectrum antifungal properties, effective against common fungi.
• Used as a topical treatment, providing localized and targeted action.

In the case of an overdose of Clotrimazole Cream, it is important to recognize that this topical medication is generally safe when used as directed. However, if a large amount is accidentally ingested, it could potentially lead to gastrointestinal discomfort or irritation. If ingestion occurs, it is advisable to contact a healthcare professional or poison control center for guidance. They can provide specific instructions and ensure appropriate measures are taken to address any potential adverse effects.

In the case of a missed dose of Clotrimazole Cream, it is important to apply the medication as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular application schedule. Do not apply extra cream to make up for the missed dose, as this may increase the risk of side effects. If you miss multiple doses, contact your healthcare provider for guidance on how to get back on track with your treatment plan. It is generally best to apply the cream at the same time each day to maintain consistent medication levels.

To use Clotrimazole Cream, clean and dry the affected area, then apply a thin layer of the cream to the skin, gently rubbing it in, usually twice a day or as directed by your healthcare provider, ensuring to follow the recommended application frequency and duration.

Following are the conditions when Clotrimazole Cream should not be used:

• Avoid using this cream if you have a known allergy to Clotrimazole or any other antifungal medications.
• Do not use this cream to treat conditions that have not been diagnosed by a healthcare professional.
• Not suitable for eyes, do not apply to the eyes or surrounding areas.
• Do not use on open wounds, severely broken skin, or large areas of skin without medical advice.
• Avoid using this cream on children without consulting a doctor.
• Do not share this medication with others, even if they have similar symptoms.
• Discontinue use and seek medical advice if you experience skin irritation, severe burning, or conditions worsen during treatment.

The side effects of Clotrimazole Cream may include:

• Skin irritation or burning at the application site
• Itching or redness
• Dry skin
• Peeling or flaking skin
• Swelling or inflammation
• Allergic reactions (such as rash, hives, or itching)
• Blistering or oozing
• Increased skin sensitivity to sunlight

Following are the precautions and warnings for Clotrimazole Cream:

• Avoid applying the cream to eyes, mouth, or open wounds. If contact occurs, rinse thoroughly with water.
• This cream is for external use only and should not be ingested or used near mucous membranes.
• Do not use this medication if you are allergic to any of its ingredients, including Clotrimazole.
• Consult a doctor if your condition does not improve after 2-4 weeks of treatment or if it worsens.
• Keep the treated area clean and dry, and avoid tight-fitting clothing that may irritate the skin.
• Do not cover the treated area with bandages or other occlusive dressings unless directed by a healthcare professional.
• Pregnant and breastfeeding women should consult their doctor before using this cream.

Following are the drug interactions for Clotrimazole Cream:

• No significant drug interactions have been reported with Clotrimazole Cream when used topically. However, it may interact with other antifungal medications if used concomitantly.
• Topical corticosteroids should be used with caution when combined with Clotrimazole Cream, as prolonged use can lead to skin thinning and increased risk of systemic absorption.
• Avoid using other topical medications at the same time as Clotrimazole Cream without consulting a healthcare professional, as it may affect the absorption and effectiveness of either product.
• The cream may enhance the absorption of other drugs applied to the same area, potentially increasing their systemic effects.
• It is advisable to avoid using other medications containing Clotrimazole or similar antifungal agents simultaneously.
• Clotrimazole Cream may increase the skin's sensitivity to sunlight, so caution should be exercised when using it with other photosensitizing drugs.
• The cream's effectiveness may be reduced if used with other products that alter the skin's pH, such as certain soaps or cleansers.

Following are the food interactions for Clotrimazole Cream:

• Avoid consuming foods with high-fat content as they may delay the absorption of Clotrimazole.
• Grapefruit and grapefruit juice should be consumed with caution as they can inhibit the CYP3A4 enzyme, potentially increasing Clotrimazole levels in the body.
• Alcoholic beverages might cause increased skin irritation or dryness when used with Clotrimazole Cream.
• Avoid applying the cream immediately after hot or spicy foods, as these can cause skin flushing and potentially increase the absorption of the medication.
• Caffeine-rich products like coffee, tea, or energy drinks might enhance the skin's sensitivity to Clotrimazole, leading to increased side effects.
• Dairy products, especially those high in fat, may interfere with the absorption of Clotrimazole, reducing its effectiveness.
• Consuming garlic supplements or large amounts of garlic-rich foods might increase Clotrimazole's anti-fungal activity, potentially causing increased skin sensitivity.
• Always follow the advice of your healthcare provider regarding dietary restrictions or modifications while using Clotrimazole Cream.

Clotrimazole Cream should be stored in a cool and dry place, preferably at room temperature, ensuring it is kept away from direct sunlight, heat, and moisture. The original container should be tightly sealed to maintain its integrity and prevent contamination. It is crucial not to store the cream in bathrooms or areas exposed to temperature fluctuations. Always check the expiration date, and dispose of any unused or expired cream responsibly, avoiding disposal in sinks or toilets. Proper disposal methods should be followed, and it is essential to keep the medication out of children's reach to prevent accidental contact or ingestion. Dispose of the cream according to local regulations or consult a pharmacist for guidance on appropriate disposal practices.

Following are the quick tips for Clotrimazole Cream:

• Clean and dry the affected area before applying the cream.
• Apply a thin layer of cream to the affected skin and nearby areas, gently rubbing it in.
• Use the cream as directed, typically twice a day, and continue treatment for the full prescribed length.
• Wash your hands after applying the cream to avoid spreading the infection.
• Avoid covering the treated area with tight-fitting clothing to allow the skin to breathe.
• Do not share your medication with others, even if they have similar symptoms.
• Store the cream at room temperature, away from direct sunlight and moisture.