Alkeris-SR (200mg) 30 Tablets

Aceclofenac 200mg Tablet primarily works by inhibiting the enzyme cyclooxygenase (COX), which is responsible for the production of prostaglandins, key mediators of inflammation. Specifically, Aceclofenac targets the COX-2 enzyme, which is primarily responsible for the generation of inflammatory prostaglandins. By blocking COX-2, Aceclofenac reduces the production of these prostaglandins, thereby decreasing inflammation, pain, and fever. This mechanism of action is shared by other non-steroidal anti-inflammatory drugs (NSAIDs), making Aceclofenac effective in managing various conditions characterized by pain and inflammation.

Aceclofenac 200mg

NSAID (Non-steroidal anti-inflammatory drug)

Tablet

The following are the uses of Aceclofenac 200mg Tablet:

• Used for relieving pain and inflammation associated with rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis.
• Used to manage post-operative pain and swelling.
• Effective in treating lower back pain and muscle pain.
• Provides relief from dental pain and inflammation.
• Used for easing pain during painful periods (dysmenorrhea).
• Helps reduce pain and inflammation in sports injuries and sprains.
• Used to alleviate pain and discomfort in acute gout attacks.

The following is the dosage regimen:

• Take 100mg twice daily in case of moderate pain
• Can be taken as per doctor's prescription

In the case of an overdose of Aceclofenac 200mg Tablets, individuals may experience symptoms such as nausea, vomiting, stomach pain, and dizziness. Prompt medical attention is necessary to manage the situation effectively. Medical professionals may induce vomiting or administer activated charcoal to prevent further absorption of the drug. Close monitoring of vital signs and supportive care are crucial during treatment. It is important to seek medical advice immediately and provide the healthcare team with details regarding the amount ingested.

In the case of a missed dose of Aceclofenac 200mg Tablet, it is important to take the medication as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one. If you miss several doses, contact your healthcare provider for advice on how to safely resume your medication and adjust your dosing schedule. It is recommended to set reminders or alarms to help you remember to take your medication on time.

To take Aceclofenac 200mg Tablet, swallow the tablet whole with a glass of water, preferably with or after food, as directed by your doctor, usually once or twice a day.

Here are the conditions and situations when Aceclofenac 200mg Tablet should not be used:

• Avoid using if you have a known allergy or hypersensitivity to Aceclofenac or other similar non-steroidal anti-inflammatory drugs (NSAIDs).
• Not recommended for individuals with active gastrointestinal bleeding or a history of gastrointestinal bleeding.
• Contraindicated in patients with severe heart failure or heart disease.
• Should not be used in patients with severe kidney disease or kidney failure.
• Avoid using if you have a history of peptic ulcers or gastrointestinal perforation.
• Not suitable for individuals with severe liver impairment or active liver disease.
• Do not use if you have recently undergone coronary artery bypass graft (CABG) surgery.
• Contraindicated in patients with a history of stroke or transient ischemic attack (TIA).
• Should not be used in individuals with bleeding disorders or those on blood-thinning medications.
• Not recommended for individuals with severe dehydration or low fluid volume.

The side effects of Aceclofenac 200mg Tablet may include:

• Stomach pain or discomfort
• Nausea and vomiting
• Diarrhea
• Constipation
• Headache
• Dizziness
• Skin rashes or itching
• Increased blood pressure

Following are the precautions and warnings for Aceclofenac 200mg Tablet:

• Avoid using this medication if you have a history of allergic reactions to Aceclofenac or other similar drugs, or any inactive ingredients in the tablet.
• Patients with gastrointestinal, cardiovascular, or liver-related diseases should exercise caution and consult a doctor before use, as it may worsen these conditions.
• This medication can increase the risk of serious gastrointestinal bleeding, especially in elderly patients. Monitor for any signs of bleeding.
• Aceclofenac may cause fluid retention and edema, so patients with heart or kidney problems should be closely monitored.
• It may mask the signs and symptoms of infection, delaying appropriate treatment. Discontinue if an infection occurs or worsens.
• Pregnant and breastfeeding women should consult their doctor before taking this medication, as it may have adverse effects on the fetus and infant.
• This medication is not recommended for children and adolescents under 18 years of age.

Following are the drug interactions for Aceclofenac 200mg Tablet:

• Lithium and diuretics may increase the risk of toxicity when taken with Aceclofenac.
• Aceclofenac can reduce the effectiveness of antihypertensive medications, including beta-blockers and ACE inhibitors.
• Potential interaction with warfarin, increasing the risk of bleeding. Regular monitoring of INR is recommended.
• May increase serum levels of digoxin, requiring careful monitoring.
• Antacids containing magnesium or aluminum may decrease the absorption of Aceclofenac.
• Concomitant use with other NSAIDs or corticosteroids can increase the risk of gastrointestinal bleeding and renal toxicity.
• Aceclofenac may enhance the anticoagulant effect of antiplatelet drugs like clopidogrel.

Following are the food interactions for Aceclofenac 200mg Tablet:

• Avoid excessive alcohol consumption while taking this medication as it can increase the risk of gastrointestinal bleeding and liver toxicity.
• Grapefruit and grapefruit juice should be consumed with caution as they may interfere with the metabolism of Aceclofenac, potentially leading to increased drug levels in the body.
• Limit the intake of fatty or greasy foods as they can slow down the absorption of Aceclofenac, affecting its effectiveness.
• Avoid high-sodium foods as Aceclofenac may increase sodium retention, and excessive sodium intake can lead to fluid retention and increased blood pressure.
• Caffeine-rich beverages like coffee and energy drinks should be limited as they can enhance the risk of caffeine-related side effects when combined with Aceclofenac.
• Consume potassium-rich foods like bananas, oranges, and spinach to maintain potassium levels, as Aceclofenac may cause potassium loss in some cases.
• Ensure adequate fluid intake to reduce the risk of kidney-related side effects, especially if you have pre-existing kidney conditions.
• Avoid spicy foods if you experience gastrointestinal discomfort or irritation while taking Aceclofenac.

Aceclofenac 200mg Tablets should be stored in a cool and dry place, preferably at room temperature (below 25°C). Keep the tablets in their original packaging, ensuring the container is tightly sealed to maintain their integrity. Protect the medication from direct exposure to sunlight, heat, and moisture, as these factors can degrade the quality of the tablets. Do not store them in the bathroom or kitchen, as these areas may have high humidity. Always check the expiration date, and dispose of any expired or unused tablets responsibly. Do not flush them or throw them into the trash; consult a pharmacist or healthcare professional for appropriate disposal methods to protect the environment. Keep the medication out of children's reach to prevent accidental consumption.

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Following are the quick tips for Aceclofenac 200mg Tablet:

• Take the tablet with or after food to prevent stomach irritation.
• Swallow the tablet whole with a full glass of water, do not crush or chew.
• Maintain a consistent schedule for taking the medication as directed by your doctor.
• Inform your doctor if you have a history of heart, liver, or kidney problems.
• Avoid alcohol consumption as it may increase the risk of stomach bleeding.
• Do not take this medication if you are allergic to any non-steroidal anti-inflammatory drugs (NSAIDs).
• If you experience any vision changes, skin rash, or unusual bleeding, contact your doctor immediately.